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These articles are provided solely for informational purposes and are not meant as medical advice . Please read the disaclaimer at the bottom of the page .
These articles are provided solely for informational purposes and are not meant as medical advice . Please read the disaclaimer at the bottom of the page .
In vitro anti-Helicobacter pylori effects of medicinal mushroom extracts, with special emphasis on the Lion's Mane mushroom, Hericium erinaceus (higher Basidiomycetes)
• Although the medicinal mushroom Hericium erinaceus is used extensively in traditional Chinese medicine to treat chronic superficial gastritis, the underlining pharmaceutical mechanism is yet to be fully understood. In this study, minimum inhibitory concentration (MIC) values of extracts prepared from the fruiting bodies of 14 mushroom species ...
Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake
• Hericium erinaceus, a well known edible mushroom, has numerous biological activities. Especially hericenones and erinacines isolated from its fruiting body stimulate nerve growth factor (NGF) synthesis, which expects H. erinaceus to have some effects on brain functions and autonomic nervous system.
Nerve growth factor-inducing activity of Hericium erinaceus in 1321N1 human astrocytoma cells
• Neurotrophic factors are essential to maintain and organize neurons functionally; thereby neurotrophic factor-like substances or their inducers are expected to be applied to the treatment of neurodegenerative diseases such as Alzheimer's disease.
Improvement of cognitive functions by oral intake of Hericium erinaceus
• Hericium erinaceus has been recognized as medical mushroom since ancient time, but its scientific evidence for human health has been still uncertain. In this study, we tested a randomized, double-blind, placebo-controlled parallel-group comparative study to evaluate the improvement of the cognitive functions by taking supplements containing fruiting body of H. erinaceus for 12 weeks.
Neurohealth Properties of Hericium erinaceus Mycelia Enriched with Erinacines
• Hericium erinaceus, an ideal culinary-medicinal mushroom, has become a well-established candidate in promoting positive brain and nerve health-related activities by inducing the nerve growth factor from its bioactive ingredient.
Hericerin derivatives activates a pan-neurotrophic pathway in central hippocampal neurons
• The traditional medicinal mushroom Hericium erinaceus is known for enhancing peripheral nerve regeneration through targeting nerve growth factor (NGF) neurotrophic activity. Here, we purified and identified biologically new active compounds from H. erinaceus, based on their ability to promote neurite outgrowth in hippocampal neurons.
Lion's Mane
• Lion's mane, Hericium erinaceus, is a culinary and medicinal mushroom. Lion’s mane appears to have neuroprotective and antioxidant properties in the brain.
Mushrooms Magnify Memory by Boosting Nerve Growth
• Active compounds in the edible Lion’s Mane mushroom can help promote neurogenesis and enhance memory, a new study reports. Preclinical trials report the compound had a significant impact on neural growth and improved memory formation. Researchers say the compound could have clinical applications in treating and preventing neurodegenerative disorders such as Alzheimer’s disease.
Ergothioneine: The mushroom-sourced antioxidant
• Synthesized only by some fungi and bacteria, this molecule is not made in the human body and can only be obtained from diet.[1] Mushrooms, by far, contain the highest levels of ergothioneine of any known food source. Ancient Egyptians believed mushrooms would grant immortality, and pharoahs proclaimed they were reserved for royalty. This article provides a detailed overview of the state of the science regarding ergothioneine. It starts by giving an background on the causes and biomarkers of oxidative stress and introduces antioxidants as a therapeutic approach.
Ergothioneine Contents in Fruiting Bodies
• The levels of ergothioneine (ERG), which have been shown to act as an excellent antioxidant, were determined in both fruiting bodies and mycelia of various mushroom species. We found that ERG accumulated at different levels in fruiting bodies of mushrooms and showed up to a 92.3-fold difference between mushrooms.
Ergothioneine: The Mushroom’s Mighty Amino Acid
• More and more, the evidence for ERG as a potential antioxidant and anti-inflammatory source is mounting. Its ability to prevent or mitigate many of the ailments we associate with the aging process has led some scientists to the nickname “longevity vitamin.”
Ergothioneine and your Brain
• Blood levels of ergothioneine have been shown to be low in patients with mild cognitive impairment and dementia [2; 4; 5]. Dementia patients with the lowest ergothioneine levels tend to show faster rates of decline and brain volume loss [6].
A Mushroom-Derived Compound That Could Change Your Life: Ergothioneine
• Citation: Amaranthus M (2023) A Mushroom-derived Compound that Could Change your Life: Ergothioneine. Food Nutr J 8: 282. https://doi.org/10.29011/2575-7091.100182
Ergothioneine: an underrecognised dietary micronutrient required for healthy ageing?
• Ergothioneine is a naturally occurring amino acid and thiol antioxidant found in high amounts in mushrooms and fermented foods. Humans and animals acquire ergothioneine from
Ergothioneine and its prospects as an anti-ageing compound
• Dietary intakes of antioxidants are crucial for longevity as they reduce the deleterious changes that are associated with free radical damage.
• Mitochondria plays central role in production of free radical associated with ageing.
• Ergothioneine is a potent antioxidant that is responsible for endogenous and exogenous antioxidant defence.
• Ergothioneine plays significant role in major ageing signalling cascades which are linearly related to the longevity of an organism.
Diet-Derived Antioxidants: The Special Case of Ergothioneine
• This article reviews what is presently known about the biological roles of the diet-derived compound ergothioneine (ET). ET seems important to humans because it is rapidly taken up from the diet by a transporter largely or completely specific for ET, and once taken up it is retained within the body for weeks or months.
Dietary Sources Of the "Longevity Vitamin" Ergothioneine
• Of more than a hundred compounds measured in the bloodstreams of thousands of individuals, the one most associated with the lowest rates of disease and death was ergothioneine. Higher blood levels were associated with lower risk of heart disease, stroke, and death from all causes put together over a period of more than 20 years.
• Although the medicinal mushroom Hericium erinaceus is used extensively in traditional Chinese medicine to treat chronic superficial gastritis, the underlining pharmaceutical mechanism is yet to be fully understood. In this study, minimum inhibitory concentration (MIC) values of extracts prepared from the fruiting bodies of 14 mushroom species ...
Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake
• Hericium erinaceus, a well known edible mushroom, has numerous biological activities. Especially hericenones and erinacines isolated from its fruiting body stimulate nerve growth factor (NGF) synthesis, which expects H. erinaceus to have some effects on brain functions and autonomic nervous system.
Nerve growth factor-inducing activity of Hericium erinaceus in 1321N1 human astrocytoma cells
• Neurotrophic factors are essential to maintain and organize neurons functionally; thereby neurotrophic factor-like substances or their inducers are expected to be applied to the treatment of neurodegenerative diseases such as Alzheimer's disease.
Improvement of cognitive functions by oral intake of Hericium erinaceus
• Hericium erinaceus has been recognized as medical mushroom since ancient time, but its scientific evidence for human health has been still uncertain. In this study, we tested a randomized, double-blind, placebo-controlled parallel-group comparative study to evaluate the improvement of the cognitive functions by taking supplements containing fruiting body of H. erinaceus for 12 weeks.
Neurohealth Properties of Hericium erinaceus Mycelia Enriched with Erinacines
• Hericium erinaceus, an ideal culinary-medicinal mushroom, has become a well-established candidate in promoting positive brain and nerve health-related activities by inducing the nerve growth factor from its bioactive ingredient.
Hericerin derivatives activates a pan-neurotrophic pathway in central hippocampal neurons
• The traditional medicinal mushroom Hericium erinaceus is known for enhancing peripheral nerve regeneration through targeting nerve growth factor (NGF) neurotrophic activity. Here, we purified and identified biologically new active compounds from H. erinaceus, based on their ability to promote neurite outgrowth in hippocampal neurons.
Lion's Mane
• Lion's mane, Hericium erinaceus, is a culinary and medicinal mushroom. Lion’s mane appears to have neuroprotective and antioxidant properties in the brain.
Mushrooms Magnify Memory by Boosting Nerve Growth
• Active compounds in the edible Lion’s Mane mushroom can help promote neurogenesis and enhance memory, a new study reports. Preclinical trials report the compound had a significant impact on neural growth and improved memory formation. Researchers say the compound could have clinical applications in treating and preventing neurodegenerative disorders such as Alzheimer’s disease.
Ergothioneine: The mushroom-sourced antioxidant
• Synthesized only by some fungi and bacteria, this molecule is not made in the human body and can only be obtained from diet.[1] Mushrooms, by far, contain the highest levels of ergothioneine of any known food source. Ancient Egyptians believed mushrooms would grant immortality, and pharoahs proclaimed they were reserved for royalty. This article provides a detailed overview of the state of the science regarding ergothioneine. It starts by giving an background on the causes and biomarkers of oxidative stress and introduces antioxidants as a therapeutic approach.
Ergothioneine Contents in Fruiting Bodies
• The levels of ergothioneine (ERG), which have been shown to act as an excellent antioxidant, were determined in both fruiting bodies and mycelia of various mushroom species. We found that ERG accumulated at different levels in fruiting bodies of mushrooms and showed up to a 92.3-fold difference between mushrooms.
Ergothioneine: The Mushroom’s Mighty Amino Acid
• More and more, the evidence for ERG as a potential antioxidant and anti-inflammatory source is mounting. Its ability to prevent or mitigate many of the ailments we associate with the aging process has led some scientists to the nickname “longevity vitamin.”
Ergothioneine and your Brain
• Blood levels of ergothioneine have been shown to be low in patients with mild cognitive impairment and dementia [2; 4; 5]. Dementia patients with the lowest ergothioneine levels tend to show faster rates of decline and brain volume loss [6].
A Mushroom-Derived Compound That Could Change Your Life: Ergothioneine
• Citation: Amaranthus M (2023) A Mushroom-derived Compound that Could Change your Life: Ergothioneine. Food Nutr J 8: 282. https://doi.org/10.29011/2575-7091.100182
Ergothioneine: an underrecognised dietary micronutrient required for healthy ageing?
• Ergothioneine is a naturally occurring amino acid and thiol antioxidant found in high amounts in mushrooms and fermented foods. Humans and animals acquire ergothioneine from
Ergothioneine and its prospects as an anti-ageing compound
• Dietary intakes of antioxidants are crucial for longevity as they reduce the deleterious changes that are associated with free radical damage.
• Mitochondria plays central role in production of free radical associated with ageing.
• Ergothioneine is a potent antioxidant that is responsible for endogenous and exogenous antioxidant defence.
• Ergothioneine plays significant role in major ageing signalling cascades which are linearly related to the longevity of an organism.
Diet-Derived Antioxidants: The Special Case of Ergothioneine
• This article reviews what is presently known about the biological roles of the diet-derived compound ergothioneine (ET). ET seems important to humans because it is rapidly taken up from the diet by a transporter largely or completely specific for ET, and once taken up it is retained within the body for weeks or months.
Dietary Sources Of the "Longevity Vitamin" Ergothioneine
• Of more than a hundred compounds measured in the bloodstreams of thousands of individuals, the one most associated with the lowest rates of disease and death was ergothioneine. Higher blood levels were associated with lower risk of heart disease, stroke, and death from all causes put together over a period of more than 20 years.




